Theophylline is used as a bronchodilator in dogs and cats with asthma or other respiratory conditions. Theophylline is a prescription medicine that is used for the treatment of airway spasms caused by asthma or chronic obstructive pulmonary disease (COPD). More information about the Inwood brand of theophylline can be found in the VIN Medical FAQ. It relaxes and opens air passages in the lungs, making it easier to breathe. Levels greater than 20 mcg/mL (111 micromol/L) are considered toxic. Theophylline was first identified as having potential for asthma as a bronchodilator in 1921 and 1922 [], but general use as a bronchodilator was not seen until the 1930s.The combination of theophylline and ephedrine was described in a 1940 publication [].Such preparations, often with a mild sedative added, dominated the market for oral theophylline products until 1975 when … I feared the medicine would no longer be available, and I'd die as a result. Seizures can also occur in severe cases of toxicity, and are considered to be a neurological emergency. Serum theophylline concentrations, blood theophylline level. The short answer is yes, you can buy theophylline online. During treatment the dog will need to be carefully monitored, both for the r… What is this test? Theophylline (400mg) mainly use for Acute severe asthma, apnoea of prematurity, asthma, obstructive airway disease, reversible airways obstruction.. and the side effects of Theophylline (400mg) are Seizures, cardiac arrhythmias, neurotoxicity, headache, irritability, nausea, anorexia, anxiety, tremors,insomnia, nervousness.. Theophylline is a chemical similar to caffeine. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells,possibly resulting in bronchodilation. 2015;16:267. Free E-newsletter Subscribe to Housecall . This means it is used daily to maintain control of your lung disease. It is important to recognize that these time intervals are much longer in the setting of overdose. Theophylline (Oral Route) Print. Therapeutic serum levels range from 10-20 mcg/mL. A close approximation of light tea can be made by soaking tea leaves in hot water for about a minute. This test measures the level of theophylline in your blood. You see, federal law requires everybody to talk to a doctor before getting any prescription medication. Some people may experience significant side effects at concentrations less than 20 mcg/mL … Theophylline is a less preferred option than inhaled corticosteroids and is recommended as a second-line choice of controller in the management of asthmatic patients. There are safer and more effective medicines available, such as inhaled steroids and leukotriene modifiers. Theophylline is a dimethylxanthine having the two methyl groups located at positions 1 and 3. There are safer and more effective medicines available. When a loading dose … Dosing can be adjusted as needed under the direction of your veterinarian, with a typical dose being 100mg twice a day. This medicine is used to prevent and treat wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, chronic bronchitis, emphysema etc. Theophylline is also used in hospital emergencies. Theophylline is ~60% protein bound and has a volume of distribution of 0.5 L/kg. Theophylline is not a rescue medicine for asthma or bronchospasm attacks. Theophylline is used for Asthma, Other Lung Diseases Causing Bronchospasms, Neonatal Apnea etc. Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. Toxic levels are considered to be higher than 20 mcg/mL; … Buy Theophylline Online. The therapeutic concentration for theophylline, when used as a bronchodilator to treat asthma, is generally considered to be 5–15 mcg/mL (28-83 micromol/L) for adults, 5–10 mcg/mL (28–55 micromol/L) for children and neonates. The authors concluded that neonates of mothers receiving theophylline products should be monitored for pharmacological effects of theophylline. Therefore, in a patient who has received no theophylline in the previous 24 hours, a loading dose of intravenous theophylline of 4.6 mg/kg (5.7 mg/kg as aminophylline), calculated on the basis of ideal body weight and administered over 30 minutes, on average, will produce a maximum post-distribution serum concentration of 10 mcg/mL with a range of 6-16 mcg/mL. Theophylline (400mg) Tablet contain theophylline as generic. The intravenous form of theophylline (aminophylline) reaches peak serum levels within 30 minutes. The doctor or nurse who gives it to you will make sure you get the correct The FDA no longer includes acute bronchospasm as an approved indication. It's sometimes used as a medicine to treat lung conditions such as asthma, chronic obstructive pulmonary disease (COPD), and bronchiolitis. It relaxes the smooth muscles of the airways leading to the lung. LiverTox . Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. Theophylline has been used as a controller in the management of mild persistent asthma, although it is usually found to be less effective than low doses of inhaled corticosteroids. Know Theophylline uses, side-effects, composition, substitutes, drug interactions, precautions, dosage, warnings only on Lybrate.com Theophylline is used to treat or prevent the symptoms of bronchial asthma, chronic bronchitis, emphysema, and other diseases involving constriction of the airways. In another study, women with asthma who used theophylline had a longer average duration of labor than did untreated women, since theophylline inhibited uterine contractions (SEDA-5, 3). Administration of the median theophylline dose required to achieve a therapeutic serum theophylline concentration in a given population may result in either sub-therapeutic or potentially toxic serum theophylline concentrations in individual patients. Follow your doctor's orders or the directions on the label. It is not one of the first medications used for long- term control of lung diseases. ... monitoring of serum Theophylline serum concentrations should be continued until it is clear that the concentration is no longer rising and has returned to non-toxic levels. Its toxicity is incre… 8. You’ll only ever be given theophylline intravenously if you’re in hospital (usually in the form of aminophylline). Its use must be monitored by direct measurement of serum theophylline levels to avoid toxicity. Theophylline works by causing muscles around the airways to relax, which helps to improve breathing. Before starting this treatment, read the manufacturer's printed information leaflet from inside the pack. It is not one of the first medications used for long-term control of lung diseases. Theophylline is used off label to treat cough caused by bronchoconstriction. It has a role as a vasodilator agent, a bronchodilator agent, a muscle relaxant, an EC 3.1.4. That's why I was such a staunch defendant of this medicine, and was upset when Theodur was no longer made, and I had to swallow generic theophylline horse pills instead. Theophylline is a drug that has been in use for asthma since the 1950's. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Theophylline is usually taken twice a day, although some doctors may prescribe just one dose a day. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Theophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a … Side Effects. How should this medicine be used? This means it is used daily to maintain control of your lung disease. It can also cause nausea, diarrhea, increase in heart rate, abnormal heart rhythms, and CNS excitation (headaches, insomnia, irritability, dizziness and lightheadedness). Theophylline is removed from the body by the liver using a system called the cytochrome p450 system. Drug information provided by: IBM Micromedex. Get useful, helpful and relevant health + wellness information . The longer answer is more complicated because there are a lot of websites out there skirting the law. Theophylline in the past and present. Other drugs that also use this system will influence the way theophylline is metabolized (depending on which drug the enzyme system will preferentially bind to). Never use theophylline in larger amounts, or for longer than prescribed. Sign up now. The following information includes only the average doses of this medicine. Note: Do not give your dog theophylline unless it has been recommended by your vet, and always follow the vet’s exact dosing recommendations. The use of theophylline is complicated by its interaction with various drugs and by the fact that it has a narrow therapeutic window. Theophyline is a long-term control medicine. Cleveland Clinic is a non-profit academic medical center. The drug is a phosphodiesterase inhibitor that dilates the airways and mainly is used in patients with chronic bronchitis, asthma or tracheal collapse. Theophylline is widely used in therapy of asthma and is not believed to cause liver injury. The leaflet will give you more information about theophylline and a full list of side-effects which you may experience from taking it. INTRODUCTION. It is given by mouth in the form of a tablet or liquid, or in hospital as an injection. The most common side effects include stomach upset and excitement. Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial. The medicine is usually given to dogs at a dosage of 4.5 – 6.8 mg/lb every 12 hours (twice daily), or 9 mg/lb once daily using 24-hour extended-release pills. Devereux G, Cotton S, Barnes P, et al. enews. How should this medicine be used? Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. It is structurally similar to caffeine and is found in green and black tea. Why is DailyMed no longer displaying pill images on the Search Results and Drug Info pages? Sections. It is available in several different forms, including capsules, tablets, an elixir, and an injection. Theophylline : Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. The dose of this medicine will be different for different patients. Answer: Theophylline is a long-term control medicine. Theophylline is a very effective bronchodilator medicine. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The following information is provided as a general guideline only. Properly discard this product when it is expired or no longer needed. For example, black tea has a higher amount of theophylline than green tea; moreover, Puer tea is beyond all tea types. It relaxes and opens air passages in the lungs, making it easier to breathe. For a given population there is no single theophylline dose that will provide both safe and effective serum concentrations for all patients. Most clinicians do not feel theophylline is warranted in the treatment of acute bronchospasm unless the patient is not responding to other treatments. Pediatric Use: Theophylline is safe and effective for the approved indications in pediatric patients. Theophylline Does this test have other names? It opens the lung’s air passages by relaxing the muscles in the lungs and chest. Any website that claims they can send you medication from another country is, therefore, skirting the law. 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